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Functional Insights From the Evolutionary Diversification of Big Defensins

Big defensins are antimicrobial polypeptides believed to be the ancestors of β-defensins, the most evolutionary conserved family of host defense peptides (HDPs) in vertebrates. Nevertheless, big defensins underwent several independent gene loss events during animal evolution, being only retained in...

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Detalles Bibliográficos
Autores principales:	Gerdol, Marco, Schmitt, Paulina, Venier, Paola, Rocha, Gustavo, Rosa, Rafael Diego, Destoumieux-Garzón, Delphine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203481/ https://www.ncbi.nlm.nih.gov/pubmed/32425943 http://dx.doi.org/10.3389/fimmu.2020.00758

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