Selection of a Clinical Lead TCR Targeting Alpha-Fetoprotein-Positive Liver Cancer Based on a Balance of Risk and Benefit

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer with a poor prognosis and limited therapeutic options. Alpha-fetoprotein (AFP), an established clinical biomarker of HCC, has been employed as an attractive target for T cell-based immunotherapy against this disease given...

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Detalles Bibliográficos
Autores principales: Luo, Xiaobing, Cui, Huijuan, Cai, Lun, Zhu, Wei, Yang, Wei-Chih, Patrick, Michael, Zhu, Shigui, Huang, Jiaqi, Yao, Xin, Yao, Yihong, He, Yukai, Ji, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203609/
https://www.ncbi.nlm.nih.gov/pubmed/32425926
http://dx.doi.org/10.3389/fimmu.2020.00623

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