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MDEHT: a multivariate approach for detecting differential expression of microRNA isoform data in RNA-sequencing studies

MOTIVATION: miRNA isoforms (isomiRs) are produced from the same arm as the archetype miRNA with a few nucleotides different at 5 and/or 3 termini. These well-conserved isomiRs are functionally important and have contributed to the evolution of miRNA genes. Accurate detection of differential expressi...

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Detalles Bibliográficos
Autores principales:	Amanullah, Md, Yu, Mengqian, Sun, Xiwei, Luo, Aoran, Zhou, Qing, Zhou, Liyuan, Hou, Ling, Wang, Wei, Lu, Weiguo, Liu, Pengyuan, Lu, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203753/ https://www.ncbi.nlm.nih.gov/pubmed/31930386 http://dx.doi.org/10.1093/bioinformatics/btaa015

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