Cargando…

Quantitative stain-free imaging and digital profiling of collagen structure reveal diverse survival of triple negative breast cancer patients

BACKGROUND: Stromal and collagen biology has a significant impact on tumorigenesis and metastasis. Collagen is a major structural extracellular matrix component in breast cancer, but its role in cancer progression is the subject of historical debate. Collagen may represent a protective layer that pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gole, Laurent, Yeong, Joe, Lim, Jeffrey Chun Tatt, Ong, Kok Haur, Han, Hao, Thike, Aye Aye, Poh, Yong Cheng, Yee, Sidney, Iqbal, Jabed, Hong, Wanjin, Lee, Bernett, Yu, Weimiao, Tan, Puay Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204022/ https://www.ncbi.nlm.nih.gov/pubmed/32375854 http://dx.doi.org/10.1186/s13058-020-01282-x

Ejemplares similares

Hypoxia-regulated carbonic anhydrase IX (CAIX) protein is an independent prognostic indicator in triple negative breast cancer
por: Ong, Chong Hui Clara, et al.
Publicado: (2022)

High Densities of Tumor-Associated Plasma Cells Predict Improved Prognosis in Triple Negative Breast Cancer
por: Yeong, Joe, et al.
Publicado: (2018)

Cancer-Testis Antigens in Triple-Negative Breast Cancer: Role and Potential Utility in Clinical Practice
por: Lam, Runyi Adeline, et al.
Publicado: (2021)

Prognostic value of CD8 + PD-1+ immune infiltrates and PDCD1 gene expression in triple negative breast cancer
por: Yeong, Joe, et al.
Publicado: (2019)

Using computer assisted image analysis to determine the optimal Ki67 threshold for predicting outcome of invasive breast cancer
por: Tay, Timothy Kwang Yong, et al.
Publicado: (2018)

A five-gene reverse transcription-PCR assay for pre-operative classification of breast fibroepithelial lesions
por: Tan, Wai Jin, et al.
Publicado: (2016)

Mutations in the epidermal growth factor receptor (EGFR) gene in triple negative breast cancer: possible implications for targeted therapy
por: Teng, Yvonne Hui-Fang, et al.
Publicado: (2011)

More microinvasive foci in larger tumours of breast ductal carcinoma in situ
por: Chen, Xiao-Yang, et al.
Publicado: (2022)

Medullary breast carcinoma: a pathogenic review and immunohistochemical study using tissue microarray
por: Lee, Ming, et al.
Publicado: (2021)

Quantitative image-based collagen structural features predict the reversibility of hepatitis C virus-induced liver fibrosis post antiviral therapies
por: Gole, Laurent, et al.
Publicado: (2023)

GRAM domain-containing protein 1B (GRAMD1B), a novel component of the JAK/STAT signaling pathway, functions in gastric carcinogenesis
por: Khanna, Puja, et al.
Publicado: (2017)

CD1d expression in renal cell carcinoma is associated with higher relapse rates, poorer cancer-specific and overall survival
por: Chong, Tsung Wen, et al.
Publicado: (2015)

NeuronCyto II: An automatic and quantitative solution for crossover neural cells in high throughput screening
por: Ong, Kok Haur, et al.
Publicado: (2016)

A comprehensive next generation sequencing tissue assay for Asian-prevalent cancers—Analytical validation and performance evaluation with clinical samples
por: Ng, Cedric Chuan-Young, et al.
Publicado: (2022)

Adipose-enriched peri-tumoral stroma, in contrast to myofibroblast-enriched stroma, prognosticates poorer survival in breast cancers
por: Lau, Hannah Si Hui, et al.
Publicado: (2023)

p53-Independent regulation of p21Waf1/Cip1 expression and senescence by PRMT6
por: Phalke, Sameer, et al.
Publicado: (2012)

Predicting Breast Cancer Events in Ductal Carcinoma In Situ (DCIS) Using Generative Adversarial Network Augmented Deep Learning Model
por: Ghose, Soumya, et al.
Publicado: (2023)

Tumor Infiltrating Lymphocytes in Multi-National Cohorts of Ductal Carcinoma In Situ (DCIS) of Breast
por: Badve, Sunil S., et al.
Publicado: (2022)

Epigenetic derepression converts PPARγ into a druggable target in triple-negative and endocrine-resistant breast cancers
por: Loo, Ser Yue, et al.
Publicado: (2021)

Automatic DNA replication tract measurement to assess replication and repair dynamics at the single-molecule level
por: Li, Longjie, et al.
Publicado: (2022)

A novel genomic panel as an adjunctive diagnostic tool for the characterization and profiling of breast Fibroepithelial lesions
por: Sim, Yirong, et al.
Publicado: (2019)

Quantitative 3D analysis of complex single border cell behaviors in coordinated collective cell migration
por: Cliffe, Adam, et al.
Publicado: (2017)

Bonney's Rapid Triple Stain
Publicado: (1908)

Whole‐exome sequencing of breast cancer, malignant peripheral nerve sheath tumor and neurofibroma from a patient with neurofibromatosis type 1
por: McPherson, John Richard, et al.
Publicado: (2015)

Predictive Factors for BRCA1 and BRCA2 Genetic Testing in an Asian Clinic-Based Population
por: Wong, Edward S. Y., et al.
Publicado: (2015)

Direct Visualization of Protease Action on Collagen Triple Helical Structure
por: Rosenblum, Gabriel, et al.
Publicado: (2010)

Immune Response in Myocardial Injury: In Situ Hybridization and Immunohistochemistry Techniques for SARS-CoV-2 Detection in COVID-19 Autopsies
por: Chong, Pek Yoon, et al.
Publicado: (2021)

Corrigendum: Immune Response in Myocardial Injury: In Situ Hybridization and Immunohistochemistry Techniques for SARS-CoV-2 Detection in COVID-19 Autopsies
por: Chong, Pek Yoon, et al.
Publicado: (2022)

Collagen IV staining pattern in bladder carcinomas: relationship to prognosis.
por: Daher, N., et al.
Publicado: (1987)

Geometric constraints alter cell arrangements within curved epithelial tissues
por: Rupprecht, Jean-Francois, et al.
Publicado: (2017)

Therapeutic and immunomodulatory potential of pazopanib in malignant phyllodes tumor
por: Ng, Dave Yong Xiang, et al.
Publicado: (2022)

Arsenic and heavy metal contents in white rice samples from rainfed paddy fields in Yangon division, Myanmar—Natural background levels?
por: Myat Soe, Aye Myint, et al.
Publicado: (2023)

A New Pentachrome Method for the Simultaneous Staining of Collagen and Sulfated Mucopolysaccharides
por: Doello, Kevin
Publicado: (2014)

Combined atezolizumab and nab-paclitaxel in the treatment of triple negative breast cancer: a meta-analysis on their efficacy and safety
por: Sharmni Vishnu, K., et al.
Publicado: (2022)

Overview of pediatric oncology and hematology in Myanmar
por: Halbert, Jay, et al.
Publicado: (2014)

Non-linearity of the collagen triple helix in solution and implications for collagen function
por: Walker, Kenneth T., et al.
Publicado: (2017)

The scaffold RhoGAP protein ARHGAP8/BPGAP1 synchronizes Rac and Rho signaling to facilitate cell migration
por: Wong, Darren Chen Pei, et al.
Publicado: (2023)

Precision Targeting of pten-Null Triple-Negative Breast Tumors Guided by Electrophilic Metabolite Sensing
por: Liu, Xuyu, et al.
Publicado: (2020)

Implementing health insurance for migrants, Thailand
por: Tangcharoensathien, Viroj, et al.
Publicado: (2017)

Post‐stroke seizure—Do the locations, types and managements of stroke matter?
por: Pande, Shrikant D., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_0bn2ojfhasuohljbc775no2bp5