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Efficacy, safety, and tolerability of combined pirfenidone and N-acetylcysteine therapy: a systematic review and meta-analysis

BACKGROUND: While antifibrotic drugs significantly decrease lung function decline in idiopathic pulmonary fibrosis (IPF), there is still an unmet need to halt disease progression. Antioxidative therapy with N-acetylcysteine (NAC) is considered a potential additional therapy that can be combined with...

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Detalles Bibliográficos
Autores principales: Shi, Hanyu, Yin, Dawei, Bonella, Francesco, Kreuter, Michael, Oltmanns, Ute, Li, Xuren, Peng, Shouchun, Wei, Luqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204217/
https://www.ncbi.nlm.nih.gov/pubmed/32380989
http://dx.doi.org/10.1186/s12890-020-1121-2