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Integrative analyses of the RNA modification machinery reveal tissue- and cancer-specific signatures

BACKGROUND: RNA modifications play central roles in cellular fate and differentiation. However, the machinery responsible for placing, removing, and recognizing more than 170 RNA modifications remains largely uncharacterized and poorly annotated, and we currently lack integrative studies that identi...

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Detalles Bibliográficos
Autores principales: Begik, Oguzhan, Lucas, Morghan C., Liu, Huanle, Ramirez, Jose Miguel, Mattick, John S., Novoa, Eva Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204298/
https://www.ncbi.nlm.nih.gov/pubmed/32375858
http://dx.doi.org/10.1186/s13059-020-02009-z