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Integrative analyses of the RNA modification machinery reveal tissue- and cancer-specific signatures
BACKGROUND: RNA modifications play central roles in cellular fate and differentiation. However, the machinery responsible for placing, removing, and recognizing more than 170 RNA modifications remains largely uncharacterized and poorly annotated, and we currently lack integrative studies that identi...
Autores principales: | Begik, Oguzhan, Lucas, Morghan C., Liu, Huanle, Ramirez, Jose Miguel, Mattick, John S., Novoa, Eva Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204298/ https://www.ncbi.nlm.nih.gov/pubmed/32375858 http://dx.doi.org/10.1186/s13059-020-02009-z |
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