Cargando…

The Active Compounds of Yixin Ningshen Tablet and Their Potential Action Mechanism in Treating Coronary Heart Disease- A Network Pharmacology and Proteomics Approach

Yixin Ningshen tablet is a CFDA-approved TCM formula for treating coronary heart disease (CHD) clinically. However, its active compounds and mechanism of action in treating CHD are unknown. In this study, a novel strategy with the combination of network pharmacology and proteomics was proposed to id...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lv, Xing, Wang, Huijun, Wu, Ruoming, Shen, Xiaoyan, Ye, Guan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204378/ https://www.ncbi.nlm.nih.gov/pubmed/32419806 http://dx.doi.org/10.1155/2020/4912395

Ejemplares similares

Simultaneous Determination of Six Active Compounds in Yixin Badiranjibuya Granules, a Traditional Chinese Medicine, by RP-HPLC-UV Method
por: Yu, Ning, et al.
Publicado: (2015)

Yixin-Shu facilitated cardiac-like differentiation of mesenchymal stem cells in vitro
por: Zhang, Jingjing, et al.
Publicado: (2018)

A Combined Phytochemistry and Network Pharmacology Approach to Reveal the Effective Substances and Mechanisms of Wei-Fu-Chun Tablet in the Treatment of Precancerous Lesions of Gastric Cancer
por: Wang, Huijun, et al.
Publicado: (2020)

Qidong Yixin Oral Liquid for Viral Myocarditis: A Systematic Review and Meta-Analysis
por: Hu, Jun, et al.
Publicado: (2020)

Exploration on the Improvement of Cognitive Function and Inflammatory Response in Perimenopausal Patients with Mild Cognitive Impairment by Self-Prepared Ningshen Prescription
por: Yang, Wei, et al.
Publicado: (2022)

Yixin-Shu Capsules Ameliorated Ischemia-Induced Heart Failure by Restoring Trx2 and Inhibiting JNK/p38 Activation
por: Xiang, Changpei, et al.
Publicado: (2021)

Analysis of the therapeutic effect of Dimu Ningshen (TCM formula) on attention deficit hyperactivity disorder based on gut microbiota and serum metabolomics
por: Tang, Kairui, et al.
Publicado: (2022)

NRF-2/HO-1 Pathway-Mediated SHOX2 Activation Is a Key Switch for Heart Rate Acceleration by Yixin-Fumai Granules
por: Zhang, Heng, et al.
Publicado: (2022)

Screening and identification of critical transcription factors involved in the protection of cardiomyocytes against hydrogen peroxide-induced damage by Yixin-shu
por: Zhang, Jingjing, et al.
Publicado: (2017)

Author Correction: Screening and identification of critical transcription factors involved in the protection of cardiomyocytes against hydrogen peroxide-induced damage by Yixin-shu
por: Zhang, Jingjing, et al.
Publicado: (2018)

Bioactive Compounds, Pharmacological Actions, and Pharmacokinetics of Genus Acacia
por: Batiha, Gaber El-Saber, et al.
Publicado: (2022)

Bioactive compounds, pharmacological actions and pharmacokinetics of Cupressus sempervirens
por: Batiha, Gaber El-Saber, et al.
Publicado: (2022)

Network Pharmacology-Based Investigation of the Therapeutic Mechanisms of Action of Danning Tablets in Nonalcoholic Fatty Liver Disease
por: Lin, Tong, et al.
Publicado: (2021)

Exploration on Molecular Mechanism of Reversal Effect of Compound Danshen Tablets on Hepatic Fibrosis Based on Network Pharmacology
por: Cao, Minling, et al.
Publicado: (2022)

Bioactive Compounds, Pharmacological Actions, and Pharmacokinetics of Wormwood (Artemisia absinthium)
por: Batiha, Gaber El-Saber, et al.
Publicado: (2020)

Retracted: Exploration on Molecular Mechanism of Reversal Effect of Compound Danshen Tablets on Hepatic Fibrosis Based on Network Pharmacology
por: and Biomechanics, Applied Bionics
Publicado: (2023)

The Study on the Mechanism of Hugan Tablets in Treating Drug-Induced Liver Injury Induced by Atorvastatin
por: Lv, Shujing, et al.
Publicado: (2021)

Efficacy and safety of Danlou tablets in traditional Chinese medicine for coronary heart disease: a systematic review and meta-analysis
por: Mao, WeiLi, et al.
Publicado: (2023)

Menogaril, an Anthracycline Compound with a Novel Mechanism of Action: Cellular Pharmacology
por: Wierzba, Konstanty, et al.
Publicado: (1990)

Proteomic Contributions to Medicinal Plant Research: From Plant Metabolism to Pharmacological Action
por: Hashiguchi, Akiko, et al.
Publicado: (2017)

The Clinical Pharmacology of Cladribine Tablets for the Treatment of Relapsing Multiple Sclerosis
por: Hermann, Robert, et al.
Publicado: (2018)

YiXin-Shu, a ShengMai-San-based traditional Chinese medicine formula, attenuates myocardial ischemia/reperfusion injury by suppressing mitochondrial mediated apoptosis and upregulating liver-X-receptor α
por: Zhao, Yichao, et al.
Publicado: (2016)

To Explore the Key Active Compounds and Therapeutic Mechanism of Guizhi Gancao Decoction in Coronary Heart Disease by Network Pharmacology and Molecular Docking
por: Yuan, Hua-jing, et al.
Publicado: (2022)

Molecular targets and mechanisms of Guanxinning tablet in treating atherosclerosis: Network pharmacology and molecular docking analysis
por: Niu, Chaofeng, et al.
Publicado: (2023)

Touchscreen Tablets: Coordinating Action and Perception for Mathematical Cognition
por: Duijzer, Carolien A. C. G., et al.
Publicado: (2017)

Network Pharmacological Study and Molecular Docking Analysis of Qiweitangping in Treating Diabetic Coronary Heart Disease
por: Liu, Tianfu, et al.
Publicado: (2021)

Network pharmacology and molecular docking-based prediction of active compounds and mechanisms of action of Cnidii Fructus in treating atopic dermatitis
por: Khan, Shakeel Ahmad, et al.
Publicado: (2022)

A meta-analysis of the Zilongjin tablets for non-small cell lung cancer and its network pharmacology of action against NSCLC and COVID-19
por: Yang, Wuxia, et al.
Publicado: (2023)

Fuling-Guizhi Herb Pair in Coronary Heart Disease: Integrating Network Pharmacology and In Vivo Pharmacological Evaluation
por: Duan, Bailu, et al.
Publicado: (2020)

The Mechanism Actions of Astragaloside IV Prevents the Progression of Hypertensive Heart Disease Based on Network Pharmacology and Experimental Pharmacology
por: Jing, Haoran, et al.
Publicado: (2021)

Clinical Study for Safety Evaluation of GXN Tablets Combined with Aspirin in Long-Term Treatment of Coronary Heart Disease
por: Zi, Mingjie, et al.
Publicado: (2021)

Effect of Dan-Lou tablets on coronary heart disease revealed by microarray analysis integrated with molecular mechanism studies
por: Li, Zhu, et al.
Publicado: (2023)

Mendelian randomization of circulating proteome identifies actionable targets in heart failure
por: Moncla, Louis-Hippolyte Minvielle, et al.
Publicado: (2022)

Decoding the Mechanism of Shixiao Powder in Treating Coronary Heart Disease Based on Network Pharmacology and Molecular Docking
por: Jiang, Zuo-min, et al.
Publicado: (2022)

Exploring Pharmacological Mechanisms of Xiang Ju Tablets in the Treatment of Allergic Rhinitis via a Network Pharmacology Approach
por: Hu, Kun xia, et al.
Publicado: (2019)

Exploring Ganweikang Tablet as a Candidate Drug for NAFLD Through Network Pharmacology Analysis and Experimental Validation
por: Ma, Chuanrui, et al.
Publicado: (2022)

Exploring the Mechanism of Action Compound-Xueshuantong Capsule in Diabetic Retinopathy Treatment Based on Network Pharmacology
por: Li, Haoran, et al.
Publicado: (2020)

Identification of Tengfu Jiangya Tablet Target Biomarkers with Quantitative Proteomic Technique
por: Xu, Jingwen, et al.
Publicado: (2017)

Determination of the synergistic anti-influenza effect of Huangqin Su tablet and Oseltamivir and investigation of mechanism of the tablet based on gut microbiota and network pharmacology
por: Cui, Xuran, et al.
Publicado: (2023)

Study on the Anti-Inflammatory Effect and Mechanism of Yuxuebi Tablet Based on Network Pharmacology
por: Hu, Xiangka, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_pfd0o2s9kg675cejkc1v6357gt