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Metabolic Reprogramming of Mouse Bone Marrow Derived Macrophages Following Erythrophagocytosis

Reticuloendothelial macrophages engulf ∼0.2 trillion senescent erythrocytes daily in a process called erythrophagocytosis (EP). This critical mechanism preserves systemic heme-iron homeostasis by regulating red blood cell (RBC) catabolism and iron recycling. Although extensive work has demonstrated...

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Detalles Bibliográficos
Autores principales: Catala, Alexis, Youssef, Lyla A., Reisz, Julie A., Dzieciatkowska, Monika, Powers, Nicholas E., Marchetti, Carlo, Karafin, Matthew, Zimring, James C., Hudson, Krystalyn E., Hansen, Kirk C., Spitalnik, Steven L., D’Alessandro, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204509/
https://www.ncbi.nlm.nih.gov/pubmed/32425810
http://dx.doi.org/10.3389/fphys.2020.00396