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Pathogenesis of Lesions Induced in Rat Lung by Chronic Tobacco Smoke Inhalation
Lesions were induced in the lungs of specific-pathogen-free F344 rats by chronic tobacco smoke exposure. Animals exposed to 7 cigarettes/day were killed after 1, 1.5, or 2 years of exposure. Parallel lifetime exposures induced pulmonary tumors in 9% of the animals. In serially killed animals, four t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
1982
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204517/ https://www.ncbi.nlm.nih.gov/pubmed/6954304 http://dx.doi.org/10.1093/jnci/69.1.117 |