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Targeted Knockout of MDA5 and TLR3 in the DF-1 Chicken Fibroblast Cell Line Impairs Innate Immune Response Against RNA Ligands

The innate immune system, which senses invading pathogens, plays a critical role as the first line of host defense. After recognition of foreign RNA ligands (e.g., RNA viruses), host cells generate an innate immune or antiviral response via the interferon-mediated signaling pathway. Retinoic acid-in...

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Detalles Bibliográficos
Autores principales:	Lee, Su Bin, Park, Young Hyun, Chungu, Kelly, Woo, Seung Je, Han, Soo Taek, Choi, Hee Jung, Rengaraj, Deivendran, Han, Jae Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204606/ https://www.ncbi.nlm.nih.gov/pubmed/32425931 http://dx.doi.org/10.3389/fimmu.2020.00678

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