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Decrease in tumor content assessed in biopsies is associated with improved treatment outcome response to pembrolizumab in patients with rare tumors

BACKGROUND: Decreased tumor content (TC) in resection specimens after neoadjuvant therapy is used to predict prognosis. We investigated whether TC assessed in biopsy specimens or the shift in TC from baseline to on-treatment can be used accordingly to predict response in patients with rare tumors wh...

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Detalles Bibliográficos
Autores principales: Tapia, Coya, Aung, Phyu P., Roy-Chowdhuri, Sinchita, Xu, Mingxuan, Ouyang, Fengying, Alshawa, Anas, Hajjar, Joud, Singh, Gopal, Yang, Vincent, Castillo, Lilibeth, Le, Hung, Murthy, Ravi, Stephen, Bettzy, Hess, Kenneth R, Wistuba, Ignacio, Naing, Aung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204618/
https://www.ncbi.nlm.nih.gov/pubmed/32303619
http://dx.doi.org/10.1136/jitc-2020-000665