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Brief recommendations on the management of adult patients with familial hypercholesterolemia during the COVID-19 pandemic

Individuals with Familial Hypercholesterolaemia (FH) are at very high risk of cardiovascular disease, which is associated with poor outcomes from coronavirus infections. COVID-19 puts strain on healthcare systems and may impair access to routine FH services. On behalf of the International Lipid Expe...

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Autores principales: Banach, Maciej, Penson, Peter E., Fras, Zlatko, Vrablik, Michal, Pella, Daniel, Reiner, Željko, Nabavi, Seyed Mohammad, Sahebkar, Amirhossein, Kayikcioglu, Meral, Daccord, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204727/
https://www.ncbi.nlm.nih.gov/pubmed/32389859
http://dx.doi.org/10.1016/j.phrs.2020.104891
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author Banach, Maciej
Penson, Peter E.
Fras, Zlatko
Vrablik, Michal
Pella, Daniel
Reiner, Željko
Nabavi, Seyed Mohammad
Sahebkar, Amirhossein
Kayikcioglu, Meral
Daccord, Magdalena
author_facet Banach, Maciej
Penson, Peter E.
Fras, Zlatko
Vrablik, Michal
Pella, Daniel
Reiner, Željko
Nabavi, Seyed Mohammad
Sahebkar, Amirhossein
Kayikcioglu, Meral
Daccord, Magdalena
author_sort Banach, Maciej
collection PubMed
description Individuals with Familial Hypercholesterolaemia (FH) are at very high risk of cardiovascular disease, which is associated with poor outcomes from coronavirus infections. COVID-19 puts strain on healthcare systems and may impair access to routine FH services. On behalf of the International Lipid Expert Panel (ILEP) and the European FH Patient Network (FH Europe), we present brief recommendations on the management of adult patients with FH during the COVID-19 pandemic. We discuss the implications of COVID-19 infections for FH patients, the importance of continuing lipid-lowering therapy where possible, issues relating to safety monitoring and service delivery. We summarise the evidence for additional benefits of statins and other lipid-lowering drugs during viral infections. The recommendations do not override in any way the individual responsibility of physicians to make appropriate and accurate decisions taking into account the condition of a given patient and the doses, rules, and regulations applicable to drugs and devices at the time of their prescription/use.
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spelling pubmed-72047272020-05-07 Brief recommendations on the management of adult patients with familial hypercholesterolemia during the COVID-19 pandemic Banach, Maciej Penson, Peter E. Fras, Zlatko Vrablik, Michal Pella, Daniel Reiner, Željko Nabavi, Seyed Mohammad Sahebkar, Amirhossein Kayikcioglu, Meral Daccord, Magdalena Pharmacol Res Article Individuals with Familial Hypercholesterolaemia (FH) are at very high risk of cardiovascular disease, which is associated with poor outcomes from coronavirus infections. COVID-19 puts strain on healthcare systems and may impair access to routine FH services. On behalf of the International Lipid Expert Panel (ILEP) and the European FH Patient Network (FH Europe), we present brief recommendations on the management of adult patients with FH during the COVID-19 pandemic. We discuss the implications of COVID-19 infections for FH patients, the importance of continuing lipid-lowering therapy where possible, issues relating to safety monitoring and service delivery. We summarise the evidence for additional benefits of statins and other lipid-lowering drugs during viral infections. The recommendations do not override in any way the individual responsibility of physicians to make appropriate and accurate decisions taking into account the condition of a given patient and the doses, rules, and regulations applicable to drugs and devices at the time of their prescription/use. Elsevier Ltd. 2020-08 2020-05-07 /pmc/articles/PMC7204727/ /pubmed/32389859 http://dx.doi.org/10.1016/j.phrs.2020.104891 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Banach, Maciej
Penson, Peter E.
Fras, Zlatko
Vrablik, Michal
Pella, Daniel
Reiner, Željko
Nabavi, Seyed Mohammad
Sahebkar, Amirhossein
Kayikcioglu, Meral
Daccord, Magdalena
Brief recommendations on the management of adult patients with familial hypercholesterolemia during the COVID-19 pandemic
title Brief recommendations on the management of adult patients with familial hypercholesterolemia during the COVID-19 pandemic
title_full Brief recommendations on the management of adult patients with familial hypercholesterolemia during the COVID-19 pandemic
title_fullStr Brief recommendations on the management of adult patients with familial hypercholesterolemia during the COVID-19 pandemic
title_full_unstemmed Brief recommendations on the management of adult patients with familial hypercholesterolemia during the COVID-19 pandemic
title_short Brief recommendations on the management of adult patients with familial hypercholesterolemia during the COVID-19 pandemic
title_sort brief recommendations on the management of adult patients with familial hypercholesterolemia during the covid-19 pandemic
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204727/
https://www.ncbi.nlm.nih.gov/pubmed/32389859
http://dx.doi.org/10.1016/j.phrs.2020.104891
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