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Viral status, immune microenvironment and immunological response to checkpoint inhibitors in hepatocellular carcinoma
BACKGROUND AND AIMS: Immune checkpoint inhibitors (ICIs) targeting the programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) pathway have clinical activity in hepatocellular carcinoma (HCC), but only a subset of patients respond to these therapies, highlighting a need for novel bi...
Autores principales: | Ho, Won Jin, Danilova, Ludmila, Lim, Su Jin, Verma, Rohan, Xavier, Stephanie, Leatherman, James M, Sztein, Marcelo B, Fertig, Elana J, Wang, Hao, Jaffee, Elizabeth, Yarchoan, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204805/ https://www.ncbi.nlm.nih.gov/pubmed/32303615 http://dx.doi.org/10.1136/jitc-2019-000394 |
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