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Opposite Roles of δ- and μ-Opioid Receptors in BACE1 Regulation and Alzheimer’s Injury

Alzheimer’s disease (AD) is characterized by amyloid plaques and neurofibrillary tangles. Substantial evidence for AD pathogenesis suggests that β-site APP cleaving enzyme 1 (BACE1) and γ-secretase enzyme initiate the amyloidogenic pathway and produces toxic Aβ peptides that prone to aggregate in th...

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Detalles Bibliográficos
Autores principales:	Xu, Yuan, Zhi, Feng, Balboni, Gianfranco, Yang, Yilin, Xia, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204847/ https://www.ncbi.nlm.nih.gov/pubmed/32425755 http://dx.doi.org/10.3389/fncel.2020.00088

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