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Antibody Production in Murine Polymicrobial Sepsis—Kinetics and Key Players

Although antigen-specific priming of antibody responses is impaired during sepsis, there is nevertheless a strong increase in IgM and IgG serum concentrations. Using colon ascendens stent peritonitis (CASP), a mouse model of polymicrobial abdominal sepsis, we observed substantial increases in IgM as...

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Detalles Bibliográficos
Autores principales: Nicolai, Oliver, Pötschke, Christian, Schmoeckel, Katrin, Darisipudi, Murthy N., van der Linde, Julia, Raafat, Dina, Bröker, Barbara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205023/
https://www.ncbi.nlm.nih.gov/pubmed/32425951
http://dx.doi.org/10.3389/fimmu.2020.00828

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