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Dynamics of IgM and IgG responses to the next generation of engineered Duffy binding protein II immunogen: Strain-specific and strain-transcending immune responses over a nine-year period
BACKGROUND: A low proportion of P. vivax-exposed individuals acquire protective strain-transcending neutralizing IgG antibodies that are able to block the interaction between the Duffy binding protein II (DBPII) and its erythrocyte-specific invasion receptor. In a recent study, a novel surface-engin...
Autores principales: | Medeiros, Camila M. P., Moreira, Eduardo U. M., Pires, Camilla V., Torres, Letícia M., Guimarães, Luiz F. F., Alves, Jéssica R. S., Lima, Bárbara A. S., Fontes, Cor J. F., Costa, Helena L., Brito, Cristiana F. A., Sousa, Tais N., Ntumngia, Francis B., Adams, John H., Kano, Flora S., Carvalho, Luzia H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205269/ https://www.ncbi.nlm.nih.gov/pubmed/32379804 http://dx.doi.org/10.1371/journal.pone.0232786 |
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