Loss of Cdc13 causes genome instability by a deficiency in replication-dependent telomere capping

In budding yeast, Cdc13, Stn1, and Ten1 form the telomere-binding heterotrimer CST complex. Here we investigate the role of Cdc13/CST in maintaining genome stability by using a Chr VII disome system that can generate recombinants, chromosome loss, and enigmatic unstable chromosomes. In cells express...

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Detalles Bibliográficos
Autores principales: Langston, Rachel E., Palazzola, Dominic, Bonnell, Erin, Wellinger, Raymund J., Weinert, Ted
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205313/
https://www.ncbi.nlm.nih.gov/pubmed/32287268
http://dx.doi.org/10.1371/journal.pgen.1008733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205313/
https://www.ncbi.nlm.nih.gov/pubmed/32287268
http://dx.doi.org/10.1371/journal.pgen.1008733

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