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Mitonuclear interactions influence Alzheimer’s disease risk

We examined the associations between mitochondrial DNA haplogroups (MT-hgs; mitochondrial haplotype groups defined by a specific combination of single nucleotide polymorphisms labeled as letters running from A to Z) and their interactions with a polygenic risk score composed of nuclear-encoded mitoc...

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Detalles Bibliográficos
Autores principales: Andrews, Shea J., Fulton-Howard, Brian, Patterson, Christopher, McFall, G Peggy, Gross, Alden, Michaelis, Elias K., Goate, Alison, Swerdlow, Russell H., Pa, Judy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205324/
https://www.ncbi.nlm.nih.gov/pubmed/31784277
http://dx.doi.org/10.1016/j.neurobiolaging.2019.09.007