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B-type natriuretic peptide is upregulated by c-Jun N-terminal kinase and contributes to septic hypotension

B-type natriuretic peptide (BNP) is secreted by ventricular cardiomyocytes in response to various types of cardiac stress and has been used as a heart failure marker. In septic patients, increased BNP suggests poor prognosis; however, no causal link has been established. Among various effects, BNP d...

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Detalles Bibliográficos
Autores principales: Hoffman, Matthew, Kyriazis, Ioannis D., Dimitriou, Alexandra, Mishra, Santosh K., Koch, Walter J., Drosatos, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205432/
https://www.ncbi.nlm.nih.gov/pubmed/32324169
http://dx.doi.org/10.1172/jci.insight.133675

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