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SARS-CoV-2 and ORF3a: Nonsynonymous Mutations, Functional Domains, and Viral Pathogenesis

The effect of the rapid accumulation of nonsynonymous mutations on the pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is not yet known. The 3a protein is unique to SARS-CoV and is essential for disease pathogenesis. Our study aimed at determining the nonsynonymous mutat...

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Detalles Bibliográficos
Autores principales:	Issa, Elio, Merhi, Georgi, Panossian, Balig, Salloum, Tamara, Tokajian, Sima
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Observation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205519/ https://www.ncbi.nlm.nih.gov/pubmed/32371472 http://dx.doi.org/10.1128/mSystems.00266-20

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