Relapsing Polychondritis with a Cobble-stone Appearance of the Tracheal Mucosa, Preceded by Posterior Reversible Encephalopathy Syndrome

A 25-year-old woman had convulsions and disturbance of consciousness. Head magnetic resonance imaging (MRI) showed punctate areas in the occipital lobes with increased signals on T2-weighted imaging. The MRI abnormalities responded well to steroid pulse therapy, so we made a diagnosis of posterior r...

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Autores principales: Ikeda, Takahide, Asano, Motochika, Kitada, Yoshihiko, Taguchi, Kouichiro, Hayashi, Yuichi, Kajita, Kazuo, Morita, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205541/
https://www.ncbi.nlm.nih.gov/pubmed/32009099
http://dx.doi.org/10.2169/internalmedicine.4095-19
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author Ikeda, Takahide
Asano, Motochika
Kitada, Yoshihiko
Taguchi, Kouichiro
Hayashi, Yuichi
Kajita, Kazuo
Morita, Hiroyuki
author_facet Ikeda, Takahide
Asano, Motochika
Kitada, Yoshihiko
Taguchi, Kouichiro
Hayashi, Yuichi
Kajita, Kazuo
Morita, Hiroyuki
author_sort Ikeda, Takahide
collection PubMed
description A 25-year-old woman had convulsions and disturbance of consciousness. Head magnetic resonance imaging (MRI) showed punctate areas in the occipital lobes with increased signals on T2-weighted imaging. The MRI abnormalities responded well to steroid pulse therapy, so we made a diagnosis of posterior reversible encephalopathy syndrome (PRES). Three months later, she developed a fever and dyspnea. Chest computed tomography revealed marked thickness of the tracheal and bronchial wall, and bronchoscopy showed a cobble-stone appearance of the tracheal mucosa, indicative of relapsing polychondritis (RPC). We consider that PRES had developed due to autoimmune vasculitis in the brain with RPC.
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spelling pubmed-72055412020-05-12 Relapsing Polychondritis with a Cobble-stone Appearance of the Tracheal Mucosa, Preceded by Posterior Reversible Encephalopathy Syndrome Ikeda, Takahide Asano, Motochika Kitada, Yoshihiko Taguchi, Kouichiro Hayashi, Yuichi Kajita, Kazuo Morita, Hiroyuki Intern Med Case Report A 25-year-old woman had convulsions and disturbance of consciousness. Head magnetic resonance imaging (MRI) showed punctate areas in the occipital lobes with increased signals on T2-weighted imaging. The MRI abnormalities responded well to steroid pulse therapy, so we made a diagnosis of posterior reversible encephalopathy syndrome (PRES). Three months later, she developed a fever and dyspnea. Chest computed tomography revealed marked thickness of the tracheal and bronchial wall, and bronchoscopy showed a cobble-stone appearance of the tracheal mucosa, indicative of relapsing polychondritis (RPC). We consider that PRES had developed due to autoimmune vasculitis in the brain with RPC. The Japanese Society of Internal Medicine 2020-02-01 2020-04-15 /pmc/articles/PMC7205541/ /pubmed/32009099 http://dx.doi.org/10.2169/internalmedicine.4095-19 Text en Copyright © 2020 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ikeda, Takahide
Asano, Motochika
Kitada, Yoshihiko
Taguchi, Kouichiro
Hayashi, Yuichi
Kajita, Kazuo
Morita, Hiroyuki
Relapsing Polychondritis with a Cobble-stone Appearance of the Tracheal Mucosa, Preceded by Posterior Reversible Encephalopathy Syndrome
title Relapsing Polychondritis with a Cobble-stone Appearance of the Tracheal Mucosa, Preceded by Posterior Reversible Encephalopathy Syndrome
title_full Relapsing Polychondritis with a Cobble-stone Appearance of the Tracheal Mucosa, Preceded by Posterior Reversible Encephalopathy Syndrome
title_fullStr Relapsing Polychondritis with a Cobble-stone Appearance of the Tracheal Mucosa, Preceded by Posterior Reversible Encephalopathy Syndrome
title_full_unstemmed Relapsing Polychondritis with a Cobble-stone Appearance of the Tracheal Mucosa, Preceded by Posterior Reversible Encephalopathy Syndrome
title_short Relapsing Polychondritis with a Cobble-stone Appearance of the Tracheal Mucosa, Preceded by Posterior Reversible Encephalopathy Syndrome
title_sort relapsing polychondritis with a cobble-stone appearance of the tracheal mucosa, preceded by posterior reversible encephalopathy syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205541/
https://www.ncbi.nlm.nih.gov/pubmed/32009099
http://dx.doi.org/10.2169/internalmedicine.4095-19
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