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An overview of COVID-19

Pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection emerged in Wuhan City, Hubei Province, China in December 2019. By Feb. 11, 2020, the World Health Organization (WHO) officially named the disease resulting from infection with SARS-CoV-2 as coronavirus disease...

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Autores principales: Shi, Yu, Wang, Gang, Cai, Xiao-peng, Deng, Jing-wen, Zheng, Lin, Zhu, Hai-hong, Zheng, Min, Yang, Bo, Chen, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Zhejiang University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205601/
https://www.ncbi.nlm.nih.gov/pubmed/32425000
http://dx.doi.org/10.1631/jzus.B2000083
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author Shi, Yu
Wang, Gang
Cai, Xiao-peng
Deng, Jing-wen
Zheng, Lin
Zhu, Hai-hong
Zheng, Min
Yang, Bo
Chen, Zhi
author_facet Shi, Yu
Wang, Gang
Cai, Xiao-peng
Deng, Jing-wen
Zheng, Lin
Zhu, Hai-hong
Zheng, Min
Yang, Bo
Chen, Zhi
author_sort Shi, Yu
collection PubMed
description Pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection emerged in Wuhan City, Hubei Province, China in December 2019. By Feb. 11, 2020, the World Health Organization (WHO) officially named the disease resulting from infection with SARS-CoV-2 as coronavirus disease 2019 (COVID-19). COVID-19 represents a spectrum of clinical manifestations that typically include fever, dry cough, and fatigue, often with pulmonary involvement. SARS-CoV-2 is highly contagious and most individuals within the population at large are susceptible to infection. Wild animal hosts and infected patients are currently the main sources of disease which is transmitted via respiratory droplets and direct contact. Since the outbreak, the Chinese government and scientific community have acted rapidly to identify the causative agent and promptly shared the viral gene sequence, and have carried out measures to contain the epidemic. Meanwhile, recent research has revealed critical aspects of SARS-CoV-2 biology and disease pathogenesis; other studies have focused on epidemiology, clinical features, diagnosis, management, as well as drug and vaccine development. This review aims to summarize the latest research findings and to provide expert consensus. We will also share ongoing efforts and experience in China, which may provide insight on how to contain the epidemic and improve our understanding of this emerging infectious disease, together with updated guidance for prevention, control, and critical management of this pandemic.
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spelling pubmed-72056012020-05-08 An overview of COVID-19 Shi, Yu Wang, Gang Cai, Xiao-peng Deng, Jing-wen Zheng, Lin Zhu, Hai-hong Zheng, Min Yang, Bo Chen, Zhi J Zhejiang Univ Sci B Review Pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection emerged in Wuhan City, Hubei Province, China in December 2019. By Feb. 11, 2020, the World Health Organization (WHO) officially named the disease resulting from infection with SARS-CoV-2 as coronavirus disease 2019 (COVID-19). COVID-19 represents a spectrum of clinical manifestations that typically include fever, dry cough, and fatigue, often with pulmonary involvement. SARS-CoV-2 is highly contagious and most individuals within the population at large are susceptible to infection. Wild animal hosts and infected patients are currently the main sources of disease which is transmitted via respiratory droplets and direct contact. Since the outbreak, the Chinese government and scientific community have acted rapidly to identify the causative agent and promptly shared the viral gene sequence, and have carried out measures to contain the epidemic. Meanwhile, recent research has revealed critical aspects of SARS-CoV-2 biology and disease pathogenesis; other studies have focused on epidemiology, clinical features, diagnosis, management, as well as drug and vaccine development. This review aims to summarize the latest research findings and to provide expert consensus. We will also share ongoing efforts and experience in China, which may provide insight on how to contain the epidemic and improve our understanding of this emerging infectious disease, together with updated guidance for prevention, control, and critical management of this pandemic. Zhejiang University Press 2020-05 /pmc/articles/PMC7205601/ /pubmed/32425000 http://dx.doi.org/10.1631/jzus.B2000083 Text en Copyright © Zhejiang University and Springer-Verlag GmbH Germany, part of Springer Nature 2020
spellingShingle Review
Shi, Yu
Wang, Gang
Cai, Xiao-peng
Deng, Jing-wen
Zheng, Lin
Zhu, Hai-hong
Zheng, Min
Yang, Bo
Chen, Zhi
An overview of COVID-19
title An overview of COVID-19
title_full An overview of COVID-19
title_fullStr An overview of COVID-19
title_full_unstemmed An overview of COVID-19
title_short An overview of COVID-19
title_sort overview of covid-19
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205601/
https://www.ncbi.nlm.nih.gov/pubmed/32425000
http://dx.doi.org/10.1631/jzus.B2000083
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