Nanofiltration of growth media supplemented with human platelet lysates for pathogen-safe xeno-free expansion of mesenchymal stromal cells

BACKGROUND AIMS: Human platelet lysate can replace fetal bovine serum (FBS) for xeno-free ex vivo expansion of mesenchymal stromal cells (MSCs), but pooling of platelet concentrates (PCs) increases risks of pathogen transmission. We evaluated the feasibility of performing nanofiltration of platelet...

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Detalles Bibliográficos
Autores principales: Barro, Lassina, Nebie, Ouada, Chen, Ming-Sheng, Wu, Yu-Wen, Koh, Mickey BC, Knutson, Folke, Watanabe, Naoto, Takahara, Masayasu, Burnouf, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Society for Cell and Gene Therapy. Published by Elsevier Inc. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205656/
https://www.ncbi.nlm.nih.gov/pubmed/32536505
http://dx.doi.org/10.1016/j.jcyt.2020.04.099

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