Cargando…

Identification of potassium and calcium channel inhibitors as modulators of polyomavirus endosomal trafficking

During virus entry, members of the Polyomaviridae transit the endolysosomal network en route to the endoplasmic reticulum (ER), from which degraded capsids escape into the cytoplasm and enter the nucleus. Emerging evidence suggests that viruses require both endosomal acidification and the correct io...

Descripción completa

Detalles Bibliográficos
Autores principales: Dobson, Samuel J., Mankouri, Jamel, Whitehouse, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205714/
https://www.ncbi.nlm.nih.gov/pubmed/32389733
http://dx.doi.org/10.1016/j.antiviral.2020.104819