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Identification of potassium and calcium channel inhibitors as modulators of polyomavirus endosomal trafficking
During virus entry, members of the Polyomaviridae transit the endolysosomal network en route to the endoplasmic reticulum (ER), from which degraded capsids escape into the cytoplasm and enter the nucleus. Emerging evidence suggests that viruses require both endosomal acidification and the correct io...
Autores principales: | Dobson, Samuel J., Mankouri, Jamel, Whitehouse, Adrian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205714/ https://www.ncbi.nlm.nih.gov/pubmed/32389733 http://dx.doi.org/10.1016/j.antiviral.2020.104819 |
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