Overexpression of peptidase inhibitor 16 attenuates angiotensin II–induced cardiac fibrosis via regulating HDAC1 of cardiac fibroblasts

Cardiac hypertrophy and fibrosis are the major causes of heart failure due to non‐ischaemia heart disease. To date, no specific therapy exists for cardiac fibrosis due to the largely unknown mechanisms of disease and lack of applicable therapeutic targets. In this study, we aimed to explore the role...

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Detalles Bibliográficos
Autores principales: Deng, Mengqing, Yang, Shuo, Ji, Yue, Lu, Yan, Qiu, Ming, Sheng, Yanhui, Sun, Wei, Kong, Xiangqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205788/
https://www.ncbi.nlm.nih.gov/pubmed/32227584
http://dx.doi.org/10.1111/jcmm.15178

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