The structure–activity relationship review of the main bioactive constituents of Morus genus plants

ABSTRACT: Morus genus plants are mainly distributed in the temperate to tropical areas over the world and include 17 species and two subspecies. Due to their excellent pharmacological activity, security in food additives and high value in the national economy, Morus genus plants have drawn more and...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Jiejing, Ruan, Jingya, Huang, Peijian, Sun, Fan, Zheng, Dandan, Zhang, Yi, Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205851/
https://www.ncbi.nlm.nih.gov/pubmed/31897975
http://dx.doi.org/10.1007/s11418-019-01383-8
_version_ 1783530318490238976
author Yan, Jiejing
Ruan, Jingya
Huang, Peijian
Sun, Fan
Zheng, Dandan
Zhang, Yi
Wang, Tao
author_facet Yan, Jiejing
Ruan, Jingya
Huang, Peijian
Sun, Fan
Zheng, Dandan
Zhang, Yi
Wang, Tao
author_sort Yan, Jiejing
collection PubMed
description ABSTRACT: Morus genus plants are mainly distributed in the temperate to tropical areas over the world and include 17 species and two subspecies. Due to their excellent pharmacological activity, security in food additives and high value in the national economy, Morus genus plants have drawn more and more attention in recent years. In the light of the references published over the last few decades, flavonoids, benzofurans, stilbenes, and Diels–Alder adducts have been reported to be the main bioactive constituents of Morus genus plants. This review summarizes the compounds with excellent bioactivities isolated from Morus genus plants as well as their structure–activity relationships (SARs), which might be useful for the further research and development of Morus genus plants. GRAPHIC ABSTRACT: [Image: see text] The aromatic heterocycles with excellent bioactivities isolated from Morus genus plants as well as their structure–activity relationships (SARs) were summarized.
format Online
Article
Text
id pubmed-7205851
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Springer Singapore
record_format MEDLINE/PubMed
spelling pubmed-72058512020-05-12 The structure–activity relationship review of the main bioactive constituents of Morus genus plants Yan, Jiejing Ruan, Jingya Huang, Peijian Sun, Fan Zheng, Dandan Zhang, Yi Wang, Tao J Nat Med Review ABSTRACT: Morus genus plants are mainly distributed in the temperate to tropical areas over the world and include 17 species and two subspecies. Due to their excellent pharmacological activity, security in food additives and high value in the national economy, Morus genus plants have drawn more and more attention in recent years. In the light of the references published over the last few decades, flavonoids, benzofurans, stilbenes, and Diels–Alder adducts have been reported to be the main bioactive constituents of Morus genus plants. This review summarizes the compounds with excellent bioactivities isolated from Morus genus plants as well as their structure–activity relationships (SARs), which might be useful for the further research and development of Morus genus plants. GRAPHIC ABSTRACT: [Image: see text] The aromatic heterocycles with excellent bioactivities isolated from Morus genus plants as well as their structure–activity relationships (SARs) were summarized. Springer Singapore 2020-01-02 2020 /pmc/articles/PMC7205851/ /pubmed/31897975 http://dx.doi.org/10.1007/s11418-019-01383-8 Text en © The Author(s) 2020, corrected publication 2020 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Yan, Jiejing
Ruan, Jingya
Huang, Peijian
Sun, Fan
Zheng, Dandan
Zhang, Yi
Wang, Tao
The structure–activity relationship review of the main bioactive constituents of Morus genus plants
title The structure–activity relationship review of the main bioactive constituents of Morus genus plants
title_full The structure–activity relationship review of the main bioactive constituents of Morus genus plants
title_fullStr The structure–activity relationship review of the main bioactive constituents of Morus genus plants
title_full_unstemmed The structure–activity relationship review of the main bioactive constituents of Morus genus plants
title_short The structure–activity relationship review of the main bioactive constituents of Morus genus plants
title_sort structure–activity relationship review of the main bioactive constituents of morus genus plants
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205851/
https://www.ncbi.nlm.nih.gov/pubmed/31897975
http://dx.doi.org/10.1007/s11418-019-01383-8
work_keys_str_mv AT yanjiejing thestructureactivityrelationshipreviewofthemainbioactiveconstituentsofmorusgenusplants
AT ruanjingya thestructureactivityrelationshipreviewofthemainbioactiveconstituentsofmorusgenusplants
AT huangpeijian thestructureactivityrelationshipreviewofthemainbioactiveconstituentsofmorusgenusplants
AT sunfan thestructureactivityrelationshipreviewofthemainbioactiveconstituentsofmorusgenusplants
AT zhengdandan thestructureactivityrelationshipreviewofthemainbioactiveconstituentsofmorusgenusplants
AT zhangyi thestructureactivityrelationshipreviewofthemainbioactiveconstituentsofmorusgenusplants
AT wangtao thestructureactivityrelationshipreviewofthemainbioactiveconstituentsofmorusgenusplants
AT yanjiejing structureactivityrelationshipreviewofthemainbioactiveconstituentsofmorusgenusplants
AT ruanjingya structureactivityrelationshipreviewofthemainbioactiveconstituentsofmorusgenusplants
AT huangpeijian structureactivityrelationshipreviewofthemainbioactiveconstituentsofmorusgenusplants
AT sunfan structureactivityrelationshipreviewofthemainbioactiveconstituentsofmorusgenusplants
AT zhengdandan structureactivityrelationshipreviewofthemainbioactiveconstituentsofmorusgenusplants
AT zhangyi structureactivityrelationshipreviewofthemainbioactiveconstituentsofmorusgenusplants
AT wangtao structureactivityrelationshipreviewofthemainbioactiveconstituentsofmorusgenusplants

Ejemplares similares