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A method for the generation of human stem cell-derived alpha cells

The generation of pancreatic cell types from renewable cell sources holds promise for cell replacement therapies for diabetes. Although most effort has focused on generating pancreatic beta cells, considerable evidence indicates that glucagon secreting alpha cells are critically involved in disease...

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Detalles Bibliográficos
Autores principales: Peterson, Quinn P., Veres, Adrian, Chen, Lihua, Slama, Michael Q., Kenty, Jennifer H. R., Hassoun, Shaimaa, Brown, Matthew R., Dou, Haiqiang, Duffy, Caden D., Zhou, Quan, Matveyenko, Aleksey V., Tyrberg, Björn, Sörhede-Winzell, Maria, Rorsman, Patrik, Melton, Douglas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205884/
https://www.ncbi.nlm.nih.gov/pubmed/32382023
http://dx.doi.org/10.1038/s41467-020-16049-3