Deletion of heat shock protein 60 in adult mouse cardiomyocytes perturbs mitochondrial protein homeostasis and causes heart failure

To maintain healthy mitochondrial enzyme content and function, mitochondria possess a complex protein quality control system, which is composed of different endogenous sets of chaperones and proteases. Heat shock protein 60 (HSP60) is one of these mitochondrial molecular chaperones and has been prop...

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Detalles Bibliográficos
Autores principales: Fan, Feifei, Duan, Yaoyun, Yang, Feili, Trexler, Christa, Wang, Hong, Huang, Lei, Li, Yali, Tang, Huayuan, Wang, Gang, Fang, Xi, Liu, Jie, Jia, Nan, Chen, Ju, Ouyang, Kunfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205885/
https://www.ncbi.nlm.nih.gov/pubmed/31209364
http://dx.doi.org/10.1038/s41418-019-0374-x

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