Contrast-enhanced ultrasound with sub-micron sized contrast agents detects insulitis in mouse models of type1 diabetes

In type1 diabetes (T1D) autoreactive T-cells infiltrate the islets of Langerhans, depleting insulin-secreting β-cells (insulitis). Insulitis arises during an asymptomatic phase, prior to clinical diagnosis of T1D. Methods to diagnose insulitis and β-cell mass changes during this asymptomatic phase a...

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Detalles Bibliográficos
Autores principales: Ramirez, David G., Abenojar, Eric, Hernandez, Christopher, Lorberbaum, David S., Papazian, Lucine A., Passman, Samantha, Pham, Vinh, Exner, Agata A., Benninger, Richard K. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206014/
https://www.ncbi.nlm.nih.gov/pubmed/32382089
http://dx.doi.org/10.1038/s41467-020-15957-8

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