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Increasing Ca(2+) in photoreceptor mitochondria alters metabolites, accelerates photoresponse recovery, and reveals adaptations to mitochondrial stress
Photoreceptors are specialized neurons that rely on Ca(2+) to regulate phototransduction and neurotransmission. Photoreceptor dysfunction and degeneration occur when intracellular Ca(2+) homeostasis is disrupted. Ca(2+) homeostasis is maintained partly by mitochondrial Ca(2+) uptake through the mito...
Autores principales: | Hutto, Rachel A., Bisbach, Celia M., Abbas, Fatima, Brock, Daniel C., Cleghorn, Whitney M., Parker, Edward D., Bauer, Benjamin H., Ge, William, Vinberg, Frans, Hurley, James B., Brockerhoff, Susan E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206026/ https://www.ncbi.nlm.nih.gov/pubmed/31371786 http://dx.doi.org/10.1038/s41418-019-0398-2 |
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