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ATF3 promotes erastin-induced ferroptosis by suppressing system Xc(–)
The amino acid antiporter system Xc(−) is important for the synthesis of glutathione (GSH) that functions to prevent lipid peroxidation and protect cells from nonapoptotic, iron-dependent death (i.e., ferroptosis). While the activity of system Xc(−) often positively correlates with the expression le...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206049/ https://www.ncbi.nlm.nih.gov/pubmed/31273299 http://dx.doi.org/10.1038/s41418-019-0380-z |