Cargando…

PIK3C3/VPS34 links T-cell autophagy to autoimmunity

Detalles Bibliográficos
Autores principales:	Yang, Guan, Van Kaer, Luc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Comment
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206076/ https://www.ncbi.nlm.nih.gov/pubmed/32382030 http://dx.doi.org/10.1038/s41419-020-2568-z

Ejemplares similares

Critical Role for Phosphatidylinositol-3 Kinase Vps34/PIK3C3 in ON-Bipolar Cells
por: He, Feng, et al.
Publicado: (2019)

An alcoholic extract of Thuja orientalis L. leaves inhibits autophagy by specifically targeting pro-autophagy PIK3C3/VPS34 complex
por: Jung, Juneyoung, et al.
Publicado: (2021)

Lighting up the fire in cold tumors to improve cancer immunotherapy by blocking the activity of the autophagy-related protein PIK3C3/VPS34
por: Janji, Bassam, et al.
Publicado: (2020)

Characterization of Atg38 and NRBF2, a fifth subunit of the autophagic Vps34/PIK3C3 complex
por: Ohashi, Yohei, et al.
Publicado: (2016)

Thymic epithelial cells require lipid kinase Vps34 for CD4 but not CD8 T cell selection
por: Postoak, J. Luke, et al.
Publicado: (2022)

Ubiquitination of the PI3-kinase VPS-34 promotes VPS-34 stability and phagosome maturation
por: Liu, Jinchao, et al.
Publicado: (2018)

Aurone derivatives as Vps34 inhibitors that modulate autophagy
por: Li, Guodong, et al.
Publicado: (2019)

Hypoxia Induces Autophagy in Human Dendritic Cells: Involvement of Class III PI3K/Vps34
por: Monaci, Sara, et al.
Publicado: (2022)

Phosphoproteomic identification of ULK substrates reveals VPS15‐dependent ULK/VPS34 interplay in the regulation of autophagy
por: Mercer, Thomas John, et al.
Publicado: (2021)

The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila
por: Juhász, Gábor, et al.
Publicado: (2008)

Cezanne promoted autophagy through PIK3C3 stabilization and PIK3C2A transcription in lung adenocarcinoma
por: Wang, Yadong, et al.
Publicado: (2023)

Long noncoding RNA BCRP3 stimulates VPS34 and autophagy activities to promote protein homeostasis and cell survival
por: Yan, Ruei-Liang, et al.
Publicado: (2022)

ULK1 induces autophagy by phosphorylating Beclin-1 and activating Vps34 lipid kinase
por: Russell, Ryan C., et al.
Publicado: (2013)

Lipid kinase PIK3C3 maintains healthy brown and white adipose tissues to prevent metabolic diseases
por: Song, Wenqiang, et al.
Publicado: (2022)

Therapeutic Targeting of Immune Cell Autophagy in Multiple Sclerosis: Russian Roulette or Silver Bullet?
por: Yang, Guan, et al.
Publicado: (2021)

Correction to: Long noncoding RNA BCRP3 stimulates VPS34 and autophagy activities to promote protein homeostasis and cell survival
por: Yan, Ruei Liang, et al.
Publicado: (2022)

The Role of Autophagy in iNKT Cell Development
por: Yang, Guan, et al.
Publicado: (2018)

VPS34 K29/K48 branched ubiquitination governed by UBE3C and TRABID regulates autophagy, proteostasis and liver metabolism
por: Chen, Yu-Hsuan, et al.
Publicado: (2021)

PKD is a kinase of Vps34 that mediates ROS-induced autophagy downstream of DAPk
por: Eisenberg-Lerner, A, et al.
Publicado: (2012)

Activation Mechanisms of the VPS34 Complexes
por: Ohashi, Yohei
Publicado: (2021)

VPS34 functions in the proximal tubule
por: Allison, Susan J.
Publicado: (2023)

Novel PtdIns(3)P-binding protein Etf1 functions as an effector of the Vps34 PtdIns 3-kinase in autophagy
por: Wurmser, Andrew E., et al.
Publicado: (2002)

Two Distinct Vps34 Phosphatidylinositol 3–Kinase Complexes Function in Autophagy and Carboxypeptidase Y Sorting inSaccharomyces cerevisiae
por: Kihara, Akio, et al.
Publicado: (2001)

Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase
por: Bago, Ruzica, et al.
Publicado: (2014)

Notoginseng Triterpenes Inhibited Autophagy in Random Flaps via the Beclin-1/VPS34/LC3 Signaling Pathway to Improve Tissue Survival
por: Huang, Zhiyang, et al.
Publicado: (2021)

HMGB1 Mediates Autophagy Dysfunction via Perturbing Beclin1-Vps34 Complex in Dopaminergic Cell Model
por: Huang, Jinsha, et al.
Publicado: (2017)

Loss of Class III Phosphoinositide 3-Kinase Vps34 Results in Cone Degeneration
por: Rajala, Ammaji, et al.
Publicado: (2020)

Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling
por: Segala, Gregory, et al.
Publicado: (2019)

Vps34 and PLD1 take center stage in nutrient signaling: their dual roles in regulating autophagy
por: Yoon, Mee-Sup
Publicado: (2015)

Therapeutic Potential of Invariant Natural Killer T Cells in Autoimmunity
por: Van Kaer, Luc, et al.
Publicado: (2018)

Vps21 Directs the PI3K-PI(3)P-Atg21-Atg16 Module to Phagophores via Vps8 for Autophagy
por: Zhao, Lei, et al.
Publicado: (2022)

Improving investment in chronic disease care in Sub-Saharan Africa is crucial for the achievement of SDG 3.4: application of the chronic care model
por: Amu, Hubert, et al.
Publicado: (2023)

Firing up the cold tumors by targeting Vps34
por: Janji, Bassam, et al.
Publicado: (2020)

VPS34 complexes from a structural perspective
por: Ohashi, Yohei, et al.
Publicado: (2019)

Ubiquitination status does not affect Vps34 degradation
por: Tang, Jing, et al.
Publicado: (2019)

hVps15, but not Ca(2+)/CaM, is required for the activity and regulation of hVps34 in mammalian cells
por: Yan, Ying, et al.
Publicado: (2009)

PI3KC2α-dependent and VPS34-independent generation of PI3P controls primary cilium-mediated autophagy in response to shear stress
por: Boukhalfa, Asma, et al.
Publicado: (2020)

Dapper1 promotes autophagy by enhancing the Beclin1-Vps34-Atg14L complex formation
por: Ma, Benyu, et al.
Publicado: (2014)

VPS34 stimulation of p62 phosphorylation for cancer progression
por: Jiang, X, et al.
Publicado: (2017)

MeHg-induced autophagy via JNK/Vps34 complex pathway promotes autophagosome accumulation and neuronal cell death
por: Lin, Tianji, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ktndq7o7kt7r8l0oshkjt5f9sh