JMJD6 modulates DNA damage response through downregulating H4K16ac independently of its enzymatic activity

The initiation and transduction of DNA damage response (DDR) occur in the context of chromatin, and modifications as well as the structure of chromatin are crucial for DDR signaling. How the profound chromatin alterations are confined to DNA lesions by epigenetic factors remains largely unclear. Her...

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Detalles Bibliográficos
Autores principales: Huo, Dawei, Chen, Hao, Cheng, Yiming, Song, Xin, Zhang, Kai, Li, Mulin Jun, Xuan, Chenghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206091/
https://www.ncbi.nlm.nih.gov/pubmed/31358914
http://dx.doi.org/10.1038/s41418-019-0397-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206091/
https://www.ncbi.nlm.nih.gov/pubmed/31358914
http://dx.doi.org/10.1038/s41418-019-0397-3

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