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JMJD6 modulates DNA damage response through downregulating H4K16ac independently of its enzymatic activity
The initiation and transduction of DNA damage response (DDR) occur in the context of chromatin, and modifications as well as the structure of chromatin are crucial for DDR signaling. How the profound chromatin alterations are confined to DNA lesions by epigenetic factors remains largely unclear. Her...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206091/ https://www.ncbi.nlm.nih.gov/pubmed/31358914 http://dx.doi.org/10.1038/s41418-019-0397-3 |