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SOX1 promotes differentiation of nasopharyngeal carcinoma cells by activating retinoid metabolic pathway
Undifferentiation is a key feature of nasopharyngeal carcinoma (NPC), which presents as a unique opportunity for intervention by differentiation therapy. In this study, we found that SOX1 inhibited proliferation, promoted differentiation, and induced senescence of NPC cells, which depended on its tr...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206110/ https://www.ncbi.nlm.nih.gov/pubmed/32382038 http://dx.doi.org/10.1038/s41419-020-2513-1 |