Cargando…
An axon-specific expression of HCN channels catalyzes fast action potential signaling in GABAergic interneurons
During high-frequency network activities, fast-spiking, parvalbumin-expressing basket cells (PV(+)-BCs) generate barrages of fast synaptic inhibition to control the probability and precise timing of action potential (AP) initiation in principal neurons. Here we describe a subcellular specialization...
Autores principales: | Roth, Fabian C., Hu, Hua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206118/ https://www.ncbi.nlm.nih.gov/pubmed/32382046 http://dx.doi.org/10.1038/s41467-020-15791-y |
Ejemplares similares
-
Complementary Tuning of Na(+) and K(+) Channel Gating Underlies Fast and Energy-Efficient Action Potentials in GABAergic Interneuron Axons
por: Hu, Hua, et al.
Publicado: (2018) -
A supercritical density of fast Na(+) channels ensures rapid propagation of action potentials in GABAergic interneuron axons
por: Hu, Hua, et al.
Publicado: (2014) -
HCN Channel Modulation of Synaptic Integration in GABAergic Interneurons in Malformed Rat Neocortex
por: Albertson, Asher J., et al.
Publicado: (2017) -
Dendritic and Axonal Wiring Optimization of Cortical GABAergic Interneurons
por: Anton-Sanchez, Laura, et al.
Publicado: (2016) -
HCN channel-mediated neuromodulation can control action potential velocity and fidelity in central axons
por: Byczkowicz, Niklas, et al.
Publicado: (2019)