Cargando…

Estimation of Conditional Mixture Weibull Distribution with Right Censored Data Using Neural Network for Time-to-Event Analysis

In this paper, we consider survival analysis with right-censored data which is a common situation in predictive maintenance and health field. We propose a model based on the estimation of two-parameter Weibull distribution conditionally to the features. To achieve this result, we describe a neural n...

Descripción completa

Detalles Bibliográficos
Autores principales: Bennis, Achraf, Mouysset, Sandrine, Serrurier, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206189/
http://dx.doi.org/10.1007/978-3-030-47426-3_53
_version_ 1783530365408772096
author Bennis, Achraf
Mouysset, Sandrine
Serrurier, Mathieu
author_facet Bennis, Achraf
Mouysset, Sandrine
Serrurier, Mathieu
author_sort Bennis, Achraf
collection PubMed
description In this paper, we consider survival analysis with right-censored data which is a common situation in predictive maintenance and health field. We propose a model based on the estimation of two-parameter Weibull distribution conditionally to the features. To achieve this result, we describe a neural network architecture and the associated loss functions that takes into account the right-censored data. We extend the approach to a finite mixture of two-parameter Weibull distributions. We first validate that our model is able to precisely estimate the right parameters of the conditional Weibull distribution on synthetic datasets. In numerical experiments on two real-word datasets (METABRIC and SEER), our model outperforms the state-of-the-art methods. We also demonstrate that our approach can consider any survival time horizon.
format Online
Article
Text
id pubmed-7206189
institution National Center for Biotechnology Information
language English
publishDate 2020
record_format MEDLINE/PubMed
spelling pubmed-72061892020-05-08 Estimation of Conditional Mixture Weibull Distribution with Right Censored Data Using Neural Network for Time-to-Event Analysis Bennis, Achraf Mouysset, Sandrine Serrurier, Mathieu Advances in Knowledge Discovery and Data Mining Article In this paper, we consider survival analysis with right-censored data which is a common situation in predictive maintenance and health field. We propose a model based on the estimation of two-parameter Weibull distribution conditionally to the features. To achieve this result, we describe a neural network architecture and the associated loss functions that takes into account the right-censored data. We extend the approach to a finite mixture of two-parameter Weibull distributions. We first validate that our model is able to precisely estimate the right parameters of the conditional Weibull distribution on synthetic datasets. In numerical experiments on two real-word datasets (METABRIC and SEER), our model outperforms the state-of-the-art methods. We also demonstrate that our approach can consider any survival time horizon. 2020-04-17 /pmc/articles/PMC7206189/ http://dx.doi.org/10.1007/978-3-030-47426-3_53 Text en © Springer Nature Switzerland AG 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Bennis, Achraf
Mouysset, Sandrine
Serrurier, Mathieu
Estimation of Conditional Mixture Weibull Distribution with Right Censored Data Using Neural Network for Time-to-Event Analysis
title Estimation of Conditional Mixture Weibull Distribution with Right Censored Data Using Neural Network for Time-to-Event Analysis
title_full Estimation of Conditional Mixture Weibull Distribution with Right Censored Data Using Neural Network for Time-to-Event Analysis
title_fullStr Estimation of Conditional Mixture Weibull Distribution with Right Censored Data Using Neural Network for Time-to-Event Analysis
title_full_unstemmed Estimation of Conditional Mixture Weibull Distribution with Right Censored Data Using Neural Network for Time-to-Event Analysis
title_short Estimation of Conditional Mixture Weibull Distribution with Right Censored Data Using Neural Network for Time-to-Event Analysis
title_sort estimation of conditional mixture weibull distribution with right censored data using neural network for time-to-event analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206189/
http://dx.doi.org/10.1007/978-3-030-47426-3_53
work_keys_str_mv AT bennisachraf estimationofconditionalmixtureweibulldistributionwithrightcensoreddatausingneuralnetworkfortimetoeventanalysis
AT mouyssetsandrine estimationofconditionalmixtureweibulldistributionwithrightcensoreddatausingneuralnetworkfortimetoeventanalysis
AT serruriermathieu estimationofconditionalmixtureweibulldistributionwithrightcensoreddatausingneuralnetworkfortimetoeventanalysis