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Multi-information Source HIN for Medical Concept Embedding
Learning low-dimensional representations for medical concepts is of great importance in improving public healthcare applications such as computer-aided diagnosis systems. Existing methods rely on Electronic Health Records (EHR) as their only information source and do not make use of abundant availab...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206250/ http://dx.doi.org/10.1007/978-3-030-47436-2_30 |
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author | Cao, Yuwei Peng, Hao Yu, Philip S. |
author_facet | Cao, Yuwei Peng, Hao Yu, Philip S. |
author_sort | Cao, Yuwei |
collection | PubMed |
description | Learning low-dimensional representations for medical concepts is of great importance in improving public healthcare applications such as computer-aided diagnosis systems. Existing methods rely on Electronic Health Records (EHR) as their only information source and do not make use of abundant available external medical knowledge, and therefore they ignore the correlations between medical concepts. To address this issue, we propose a novel multi-information source Heterogeneous Information Network (HIN) to model EHR while incorporating external medical knowledge including ICD-9-CM and MeSH for an enriched network schema. Our model is well aware of the structure of EHR as well as the correlations between medical concepts it refers to, and learns semantically reflective medical concept embeddings. In experiments, our model outperforms unsupervised baselines in a variety of medical data mining tasks. |
format | Online Article Text |
id | pubmed-7206250 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
record_format | MEDLINE/PubMed |
spelling | pubmed-72062502020-05-08 Multi-information Source HIN for Medical Concept Embedding Cao, Yuwei Peng, Hao Yu, Philip S. Advances in Knowledge Discovery and Data Mining Article Learning low-dimensional representations for medical concepts is of great importance in improving public healthcare applications such as computer-aided diagnosis systems. Existing methods rely on Electronic Health Records (EHR) as their only information source and do not make use of abundant available external medical knowledge, and therefore they ignore the correlations between medical concepts. To address this issue, we propose a novel multi-information source Heterogeneous Information Network (HIN) to model EHR while incorporating external medical knowledge including ICD-9-CM and MeSH for an enriched network schema. Our model is well aware of the structure of EHR as well as the correlations between medical concepts it refers to, and learns semantically reflective medical concept embeddings. In experiments, our model outperforms unsupervised baselines in a variety of medical data mining tasks. 2020-04-17 /pmc/articles/PMC7206250/ http://dx.doi.org/10.1007/978-3-030-47436-2_30 Text en © Springer Nature Switzerland AG 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Article Cao, Yuwei Peng, Hao Yu, Philip S. Multi-information Source HIN for Medical Concept Embedding |
title | Multi-information Source HIN for Medical Concept Embedding |
title_full | Multi-information Source HIN for Medical Concept Embedding |
title_fullStr | Multi-information Source HIN for Medical Concept Embedding |
title_full_unstemmed | Multi-information Source HIN for Medical Concept Embedding |
title_short | Multi-information Source HIN for Medical Concept Embedding |
title_sort | multi-information source hin for medical concept embedding |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206250/ http://dx.doi.org/10.1007/978-3-030-47436-2_30 |
work_keys_str_mv | AT caoyuwei multiinformationsourcehinformedicalconceptembedding AT penghao multiinformationsourcehinformedicalconceptembedding AT yuphilips multiinformationsourcehinformedicalconceptembedding |