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Multi-information Source HIN for Medical Concept Embedding

Learning low-dimensional representations for medical concepts is of great importance in improving public healthcare applications such as computer-aided diagnosis systems. Existing methods rely on Electronic Health Records (EHR) as their only information source and do not make use of abundant availab...

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Detalles Bibliográficos
Autores principales: Cao, Yuwei, Peng, Hao, Yu, Philip S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206250/
http://dx.doi.org/10.1007/978-3-030-47436-2_30
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author Cao, Yuwei
Peng, Hao
Yu, Philip S.
author_facet Cao, Yuwei
Peng, Hao
Yu, Philip S.
author_sort Cao, Yuwei
collection PubMed
description Learning low-dimensional representations for medical concepts is of great importance in improving public healthcare applications such as computer-aided diagnosis systems. Existing methods rely on Electronic Health Records (EHR) as their only information source and do not make use of abundant available external medical knowledge, and therefore they ignore the correlations between medical concepts. To address this issue, we propose a novel multi-information source Heterogeneous Information Network (HIN) to model EHR while incorporating external medical knowledge including ICD-9-CM and MeSH for an enriched network schema. Our model is well aware of the structure of EHR as well as the correlations between medical concepts it refers to, and learns semantically reflective medical concept embeddings. In experiments, our model outperforms unsupervised baselines in a variety of medical data mining tasks.
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spelling pubmed-72062502020-05-08 Multi-information Source HIN for Medical Concept Embedding Cao, Yuwei Peng, Hao Yu, Philip S. Advances in Knowledge Discovery and Data Mining Article Learning low-dimensional representations for medical concepts is of great importance in improving public healthcare applications such as computer-aided diagnosis systems. Existing methods rely on Electronic Health Records (EHR) as their only information source and do not make use of abundant available external medical knowledge, and therefore they ignore the correlations between medical concepts. To address this issue, we propose a novel multi-information source Heterogeneous Information Network (HIN) to model EHR while incorporating external medical knowledge including ICD-9-CM and MeSH for an enriched network schema. Our model is well aware of the structure of EHR as well as the correlations between medical concepts it refers to, and learns semantically reflective medical concept embeddings. In experiments, our model outperforms unsupervised baselines in a variety of medical data mining tasks. 2020-04-17 /pmc/articles/PMC7206250/ http://dx.doi.org/10.1007/978-3-030-47436-2_30 Text en © Springer Nature Switzerland AG 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Cao, Yuwei
Peng, Hao
Yu, Philip S.
Multi-information Source HIN for Medical Concept Embedding
title Multi-information Source HIN for Medical Concept Embedding
title_full Multi-information Source HIN for Medical Concept Embedding
title_fullStr Multi-information Source HIN for Medical Concept Embedding
title_full_unstemmed Multi-information Source HIN for Medical Concept Embedding
title_short Multi-information Source HIN for Medical Concept Embedding
title_sort multi-information source hin for medical concept embedding
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206250/
http://dx.doi.org/10.1007/978-3-030-47436-2_30
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