The preventive effect of atorvastatin on liver fibrosis in the bile duct ligation rats via antioxidant activity and down-regulation of Rac1 and NOX1

OBJECTIVE(S): Atorvastatin is a cholesterol-lowering agent capable of inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase. Recent studies have demonstrated new facets of atorvastatin, such as antioxidant and anti-fibrotic properties. We investigated the effect of atorvastatin on hepatic injur...

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Detalles Bibliográficos
Autores principales: Ghoreshi, Zohreh-al-sadat, Kabirifar, Razieh, Khodarahmi, Ameneh, Karimollah, Alireza, Moradi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206847/
https://www.ncbi.nlm.nih.gov/pubmed/32395205
http://dx.doi.org/10.22038/IJBMS.2019.33663.8047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206847/
https://www.ncbi.nlm.nih.gov/pubmed/32395205
http://dx.doi.org/10.22038/IJBMS.2019.33663.8047

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