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The preventive effect of atorvastatin on liver fibrosis in the bile duct ligation rats via antioxidant activity and down-regulation of Rac1 and NOX1
OBJECTIVE(S): Atorvastatin is a cholesterol-lowering agent capable of inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase. Recent studies have demonstrated new facets of atorvastatin, such as antioxidant and anti-fibrotic properties. We investigated the effect of atorvastatin on hepatic injur...
Autores principales: | Ghoreshi, Zohreh-al-sadat, Kabirifar, Razieh, Khodarahmi, Ameneh, Karimollah, Alireza, Moradi, Ali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206847/ https://www.ncbi.nlm.nih.gov/pubmed/32395205 http://dx.doi.org/10.22038/IJBMS.2019.33663.8047 |
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