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Characterization of tumor mutation burden, PD-L1 and DNA repair genes to assess relationship to immune checkpoint inhibitors response in metastatic renal cell carcinoma

BACKGROUND: Immune checkpoint inhibitors (ICIs) have expanded treatment options for metastatic renal cell carcinoma (mRCC); however, there are limited predictive biomarkers for response to ICIs in this indication, with programmed death-ligand 1 (PD-L1) status demonstrating little predictive utility...

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Detalles Bibliográficos
Autores principales:	Labriola, Matthew Kyle, Zhu, Jason, Gupta, Rajan, McCall, Shannon, Jackson, Jennifer, Kong, Eric F, White, James R, Cerqueira, Gustavo, Gerding, Kelly, Simmons, John K, George, Daniel, Zhang, Tian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2020
Materias:	Immunotherapy Biomarkers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206964/ https://www.ncbi.nlm.nih.gov/pubmed/32221016 http://dx.doi.org/10.1136/jitc-2019-000319

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