Cargando…
Immunosuppressant indulges EBV reactivation and related lymphoproliferative disease by inhibiting Vδ2(+) T cells activities after hematopoietic transplantation for blood malignancies
BACKGROUND: Following the extensive use of immunosuppressive drugs in the clinic, immunosuppression-associated side effects have received increasing attention. Epstein-Barr virus (EBV) reactivation and related lymphoproliferative diseases (LPD) are the lethal complications observed after allogeneic...
Autores principales: | Liu, Jiangying, Gao, Haitao, Xu, Lan-Ping, Mo, Xiao-Dong, Liu, Ruoyang, Liang, Shuang, Wu, Ning, Wang, Ming, Wang, Zhidong, Chang, Ying-Jun, Wang, Yu, Zhang, Xiao-Hui, Huang, Xiao-Jun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206968/ https://www.ncbi.nlm.nih.gov/pubmed/32221014 http://dx.doi.org/10.1136/jitc-2019-000208 |
Ejemplares similares
-
Induction of EBV latent membrane protein-2A (LMP2A)-specific T cells and construction of individualized TCR-engineered T cells for EBV-associated malignancies
por: Zhang, Chaoting, et al.
Publicado: (2021) -
'Off-the-shelf’ allogeneic antigen-specific adoptive T-cell therapy for the treatment of multiple EBV-associated malignancies
por: Sinha, Debottam, et al.
Publicado: (2021) -
Blockade of AIM2 inflammasome or α1-AR ameliorates IL-1β release and macrophage-mediated immunosuppression induced by CAR-T treatment
por: Liu, Dan, et al.
Publicado: (2021) -
Costimulation of γδTCR and TLR7/8 promotes Vδ2 T-cell antitumor activity by modulating mTOR pathway and APC function
por: Wang, Huaishan, et al.
Publicado: (2021) -
Δ133p53α enhances metabolic and cellular fitness of TCR-engineered T cells and promotes superior antitumor immunity
por: Legscha, Kevin Jan, et al.
Publicado: (2021)