EpCAM-high liver cancer stem cells resist natural killer cell–mediated cytotoxicity by upregulating CEACAM1

BACKGROUND: Natural killer (NK) cells can recognize and kill cancer cells directly, but their activity can be attenuated by various inhibitory molecules expressed on the surface. The expression of epithelial cell adhesion molecule (EpCAM), a potential marker for cancer stem cells (CSCs), is known to...

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Detalles Bibliográficos
Autores principales: Park, Dong Jun, Sung, Pil Soo, Kim, Jung-Hee, Lee, Gil Won, Jang, Jeong Won, Jung, Eun Sun, Bae, Si Hyun, Choi, Jong Young, Yoon, Seung Kew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206970/
https://www.ncbi.nlm.nih.gov/pubmed/32221015
http://dx.doi.org/10.1136/jitc-2019-000301

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