Cargando…

Skimmin Improves Insulin Resistance via Regulating the Metabolism of Glucose: In Vitro and In Vivo Models

Skimmin is the major pharmacologically active component present in Hydrangea paniculata, in the traditional Chinese medicine as an anti-inflammatory agent, and its anti-inflammation and anti-diabetic effect has had been studied in previous studies. The metabolism of glucose plays an important role i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Guoqiang, Cai, Xin, He, Lingmin, Qin, Dingmei, Li, Hongwen, Fan, Xiaoming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207098/ https://www.ncbi.nlm.nih.gov/pubmed/32425786 http://dx.doi.org/10.3389/fphar.2020.00540

Ejemplares similares

Brain Transport Profiles of Ginsenoside Rb(1) by Glucose Transporter 1: In Vitro and in Vivo
por: Wang, Yu-Zhu, et al.
Publicado: (2018)

Skimmin, a Coumarin from Hydrangea paniculata, Slows down the Progression of Membranous Glomerulonephritis by Anti-Inflammatory Effects and Inhibiting Immune Complex Deposition
por: Zhang, Sen, et al.
Publicado: (2013)

Emodin Attenuates Lipopolysaccharide-Induced Acute Liver Injury via Inhibiting the TLR4 Signaling Pathway in vitro and in vivo
por: Ding, Yan, et al.
Publicado: (2018)

Evaluation of commonly used cardiovascular drugs in inhibiting vonoprazan metabolism in vitro and in vivo
por: Wang, Yiran, et al.
Publicado: (2022)

Methazolamide Is a New Hepatic Insulin Sensitizer That Lowers Blood Glucose In Vivo
por: Konstantopoulos, Nicky, et al.
Publicado: (2012)

Propofol inhibits neuroinflammation and metabolic reprogramming in microglia in vitro and in vivo
por: Guan, Shuyuan, et al.
Publicado: (2023)

Studies on the inhibitory effect of isavuconazole on flumatinib metabolism in vitro and in vivo
por: Liu, Ya-nan, et al.
Publicado: (2023)

Tongluo Yishen Decoction Ameliorates Renal Fibrosis via NLRP3-Mediated Pyroptosis In Vivo and In Vitro
por: Jia, Qi, et al.
Publicado: (2022)

Co-Crystal of Rosiglitazone With Berberine Ameliorates Hyperglycemia and Insulin Resistance Through the PI3K/AKT/TXNIP Pathway In Vivo and In Vitro
por: He, Qichen, et al.
Publicado: (2022)

Shuangyu Tiaozhi decoction alleviates non-alcoholic fatty liver disease by improving lipid deposition, insulin resistance, and inflammation in vitro and in vivo
por: Yin, Guoliang, et al.
Publicado: (2022)

Effects of Taxifolin on Osteoclastogenesis in vitro and in vivo
por: Cai, Cong, et al.
Publicado: (2018)

A SGLT2 Inhibitor Dapagliflozin Alleviates Diabetic Cardiomyopathy by Suppressing High Glucose-Induced Oxidative Stress in vivo and in vitro
por: Xing, Yu-jie, et al.
Publicado: (2021)

Combined Use of Astragalus Polysaccharide and Berberine Attenuates Insulin Resistance in IR-HepG2 Cells via Regulation of the Gluconeogenesis Signaling Pathway
por: Mao, Zhu-Jun, et al.
Publicado: (2019)

Cyclovirobuxine D Ameliorates Experimental Diabetic Cardiomyopathy by Inhibiting Cardiomyocyte Pyroptosis via NLRP3 in vivo and in vitro
por: Gao, Ge, et al.
Publicado: (2022)

Linezolid and Its Immunomodulatory Effect: In Vitro and In Vivo Evidence
por: Wang, Jin, et al.
Publicado: (2019)

A Sensitive LC-MS/MS Method for the Simultaneous Determination of Skimmin, a Potential Agent for Treating Postpartum Stroke, and Its Metabolite Umbelliferone in Rat Plasma
por: Sun, Yaqiong, et al.
Publicado: (2023)

In Vivo Efficacy and Metabolism of the Antimalarial Cycleanine and Improved In Vitro Antiplasmodial Activity of Semisynthetic Analogues
por: Uche, Fidelia Ijeoma, et al.
Publicado: (2021)

Changes in Glucose and Fat Metabolism in Response to the Administration of a Hepato-Preferential Insulin Analog
por: Edgerton, Dale S., et al.
Publicado: (2014)

Mogroside IIe Ameliorates Cardiomyopathy by Suppressing Cardiomyocyte Apoptosis in a Type 2 Diabetic Model
por: Cai, Xin, et al.
Publicado: (2021)

Fibroblast Growth Factor-1 Improves Insulin Resistance via Repression of JNK-Mediated Inflammation
por: Fan, Lei, et al.
Publicado: (2019)

Uncovering the pharmacological mechanisms of Zizhu ointment against diabetic ulcer by integrating network analysis and experimental evaluation in vivo and in vitro
por: Wang, Jie, et al.
Publicado: (2022)

Hydroxychloroquine Improves Obesity-Associated Insulin Resistance and Hepatic Steatosis by Regulating Lipid Metabolism
por: Qiao, Xin, et al.
Publicado: (2019)

Berberine Alleviates Insulin Resistance and Inflammation via Inhibiting the LTB4–BLT1 Axis
por: Gong, Minmin, et al.
Publicado: (2021)

Effect of Konjac Mannan Oligosaccharides on Glucose Homeostasis via the Improvement of Insulin and Leptin Resistance In Vitro and In Vivo
por: Zhu, Di, et al.
Publicado: (2019)

The Protective Effect of Magnolol in Osteoarthritis: In vitro and in vivo Studies
por: Hu, Zhi-Chao, et al.
Publicado: (2019)

Inhibition of Caffeine Metabolism by Apiaceous and Rutaceae Families of Plant Products in Humans: In Vivo and In Vitro Studies
por: Alehaideb, Zeyad, et al.
Publicado: (2021)

Effects of Sodium-Glucose Cotransporter 2 Inhibitors on Water and Sodium Metabolism
por: Tang, Jun, et al.
Publicado: (2022)

Inhibition of Glucose-6-Phosphate Dehydrogenase Reverses Cisplatin Resistance in Lung Cancer Cells via the Redox System
por: Hong, Weipeng, et al.
Publicado: (2018)

Glucose Metabolism Reprogramming of Regulatory T Cells in Concanavalin A-Induced Hepatitis
por: Huang, Chen, et al.
Publicado: (2021)

15, 16-Dihydrotanshinone I Inhibits Hemangiomas through Inducing Pro-apoptotic and Anti-angiogenic Mechanisms in Vitro and in Vivo
por: Cai, Yihong, et al.
Publicado: (2018)

Geniposide Alleviates Isoproterenol-Induced Cardiac Fibrosis Partially via SIRT1 Activation in vivo and in vitro
por: Li, Ning, et al.
Publicado: (2018)

Epigallocatechin-3-Gallate Ameliorates Glucocorticoid-Induced Osteoporosis of Rats in Vivo and in Vitro
por: Liu, Shengye, et al.
Publicado: (2018)

Hyperoside Protected Against Oxidative Stress-Induced Liver Injury via the PHLPP2-AKT-GSK-3β Signaling Pathway In Vivo and In Vitro
por: Xing, Haiyan, et al.
Publicado: (2020)

Alantolactone Improves Prolonged Exposure of Interleukin-6-Induced Skeletal Muscle Inflammation Associated Glucose Intolerance and Insulin Resistance
por: Kim, Minjee, et al.
Publicado: (2017)

Cheong-sang-bang-pung-san alleviated hepatic lipid accumulation by regulating lipid metabolism in vitro and in vivo
por: Kang, Yun-Mi, et al.
Publicado: (2023)

Shen-Zhi-Ling oral liquid ameliorates cerebral glucose metabolism disorder in early AD via insulin signal transduction pathway in vivo and in vitro
por: Qin, Gaofeng, et al.
Publicado: (2021)

Salvianolic Acid A Has Anti-Osteoarthritis Effect In Vitro and In Vivo
por: Wu, Yifan, et al.
Publicado: (2020)

Sanye Tablet Ameliorates Insulin Resistance and Dysregulated Lipid Metabolism in High-Fat Diet-Induced Obese Mice
por: Yao, Minghe, et al.
Publicado: (2021)

Canagliflozin alleviates high glucose-induced peritoneal fibrosis via HIF-1α inhibition
por: Wang, Jian, et al.
Publicado: (2023)

Immune and Metabolic Regulation Mechanism of Dangguiliuhuang Decoction against Insulin Resistance and Hepatic Steatosis
por: Cao, Hui, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_6kc0lm1gft7lkqpujthm9tovbs