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SUN-657 The Effect of Simvastatin on Glucose Metabolism in Primary Human Muscle Cells
Statin use, especially treatment with simvastatin, is associated with impaired insulin secretion and whole-body insulin sensitivity, and increased risk for T2D. Here, we investigated the direct effects of lactone- and acid-forms of simvastatin on glucose metabolism in primary human skeletal muscle c...
Autores principales: | Mäkinen, Selina, Datta-Sengupta, Neeta, Nguyen, Yen, Kyrylenko, Petro, Laakso, Markku, Koistinen, Heikki A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207281/ http://dx.doi.org/10.1210/jendso/bvaa046.1677 |
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