SAT-655 Bile Acid Sequestration Synergistically Accelerates Glucagon Receptor-Stimulated Body Weight Loss in Diet-Induced Obese Mice

Glucagon, an essential regulator of glucose and lipid metabolism, also promotes weight loss in obese mice. We have shown that hepatic Farnesoid X Receptor (FXR, a bile acid receptor) and bile acids (BA) play an important role in the anti-obesity effect of glucagon in mice. Specifically, glucagon-rec...

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Detalles Bibliográficos
Autores principales: Kim, Teayoun, Nason, Shelly R, Antipenko, Jessica, Presedo, Natalie, Finan, Brian, DiMarchi, Richard D, Habegger, Kirk M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Diabetes Mellitus and Glucose Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207330/
http://dx.doi.org/10.1210/jendso/bvaa046.1106

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