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SUN-569 The Normalization of Sleep Duratioin as a Factor of Glyhemoglobin Reducing
Sleep deprivation is an important risk factor of the metabolic disorder. According to the systematic review published in the Circulation there are a lot of data from epidemiological, clinical and experimental researches which confirm this fact. The goal of our research was to assess the level of gly...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207402/ http://dx.doi.org/10.1210/jendso/bvaa046.1354 |
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author | Dzherieva, Irina Volkova, Natalya Komurdzhyntcs, Maria Davidenko, Ilia Ganenko, Lilia Plyashkevich, Maria |
author_facet | Dzherieva, Irina Volkova, Natalya Komurdzhyntcs, Maria Davidenko, Ilia Ganenko, Lilia Plyashkevich, Maria |
author_sort | Dzherieva, Irina |
collection | PubMed |
description | Sleep deprivation is an important risk factor of the metabolic disorder. According to the systematic review published in the Circulation there are a lot of data from epidemiological, clinical and experimental researches which confirm this fact. The goal of our research was to assess the level of glycohemoglibin after the normalization of sleep duration. 24 patients with diabetes mellitus type2 (19 females and 7 males, average age 58.7 ±1.3 yer) were included in the research. Diabetes mellitus type 2 duration was 9.5 years. Criteria excluded were myocardial infarction, stroke, sleep apnea, oncological diseases and depression. To exclude depression we used the questionnaires: Center for Epidemiological Studies Depression Scale and The Hospital Anxiety And Depression Scale. To exclude sleep apnea we used questionnaire STOP-Bang score. The sleep duration was assessed by the patients self-reports. Glycohemoglibin was determined by Immunoinhibition Method Cobas 6000, Roche Diagnostics. The sleep duration was corrected by cognitive behavioral therapy. For statistic assess of the results we used the method Wilcoxon F. Results: At the beginning of the treatment the level of glyhemoglobin was 7.8% and the sleep duration was 6.4 hours.The included patients were treated by cognitive behavioral therapy for 6 months without changing other kinds of therapy. The sleep duration significantly(P=-0.35) enlarged until 7.5±0.2 hours and the level of glyhemoglobin was lowered by 0.4% significantly (P=0.47). The improving of sleep duration can successfully reduce the level of glyhemoglobin in diabetes mellitus type 2 without any intervention at glycemia and could contribute to the prevention of diabetes complications. |
format | Online Article Text |
id | pubmed-7207402 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-72074022020-05-12 SUN-569 The Normalization of Sleep Duratioin as a Factor of Glyhemoglobin Reducing Dzherieva, Irina Volkova, Natalya Komurdzhyntcs, Maria Davidenko, Ilia Ganenko, Lilia Plyashkevich, Maria J Endocr Soc Cardiovascular Endocrinology Sleep deprivation is an important risk factor of the metabolic disorder. According to the systematic review published in the Circulation there are a lot of data from epidemiological, clinical and experimental researches which confirm this fact. The goal of our research was to assess the level of glycohemoglibin after the normalization of sleep duration. 24 patients with diabetes mellitus type2 (19 females and 7 males, average age 58.7 ±1.3 yer) were included in the research. Diabetes mellitus type 2 duration was 9.5 years. Criteria excluded were myocardial infarction, stroke, sleep apnea, oncological diseases and depression. To exclude depression we used the questionnaires: Center for Epidemiological Studies Depression Scale and The Hospital Anxiety And Depression Scale. To exclude sleep apnea we used questionnaire STOP-Bang score. The sleep duration was assessed by the patients self-reports. Glycohemoglibin was determined by Immunoinhibition Method Cobas 6000, Roche Diagnostics. The sleep duration was corrected by cognitive behavioral therapy. For statistic assess of the results we used the method Wilcoxon F. Results: At the beginning of the treatment the level of glyhemoglobin was 7.8% and the sleep duration was 6.4 hours.The included patients were treated by cognitive behavioral therapy for 6 months without changing other kinds of therapy. The sleep duration significantly(P=-0.35) enlarged until 7.5±0.2 hours and the level of glyhemoglobin was lowered by 0.4% significantly (P=0.47). The improving of sleep duration can successfully reduce the level of glyhemoglobin in diabetes mellitus type 2 without any intervention at glycemia and could contribute to the prevention of diabetes complications. Oxford University Press 2020-05-08 /pmc/articles/PMC7207402/ http://dx.doi.org/10.1210/jendso/bvaa046.1354 Text en © Endocrine Society 2020. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Cardiovascular Endocrinology Dzherieva, Irina Volkova, Natalya Komurdzhyntcs, Maria Davidenko, Ilia Ganenko, Lilia Plyashkevich, Maria SUN-569 The Normalization of Sleep Duratioin as a Factor of Glyhemoglobin Reducing |
title | SUN-569 The Normalization of Sleep Duratioin as a Factor of Glyhemoglobin Reducing |
title_full | SUN-569 The Normalization of Sleep Duratioin as a Factor of Glyhemoglobin Reducing |
title_fullStr | SUN-569 The Normalization of Sleep Duratioin as a Factor of Glyhemoglobin Reducing |
title_full_unstemmed | SUN-569 The Normalization of Sleep Duratioin as a Factor of Glyhemoglobin Reducing |
title_short | SUN-569 The Normalization of Sleep Duratioin as a Factor of Glyhemoglobin Reducing |
title_sort | sun-569 the normalization of sleep duratioin as a factor of glyhemoglobin reducing |
topic | Cardiovascular Endocrinology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207402/ http://dx.doi.org/10.1210/jendso/bvaa046.1354 |
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