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SAT-454 A Novel Role of Thyroid Hormone Receptor in Synaptic Plasticity in Cerebellar Purkinje Cells

Thyroid hormone (TH) is essential for the development and the maintenance of the brain function. TH action is mediated by TH receptor (TR). TR binds to a specific DNA sequence on TH-target genes and thus functions as a ligand-dependent transcription factor. In thyroid diseases such as congenital hyp...

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Detalles Bibliográficos
Autores principales: Ninomiya, Ayane, Hosoi, Nobutake, Kokubo, Michifumi, Amano, Izuki, Haijima, Asahi, Miyazaki, Wataru, Hirai, Hirokazu, Koibuchi, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207436/
http://dx.doi.org/10.1210/jendso/bvaa046.1706